Application

Single Cell Transcriptomics

Single cell transcriptomics unlocks detailed information about the complexity of cells and has transformed our understanding of cellular biology. Many single-cell phenotyping applications rely on surveying many cells in a population to get a full picture of the cellular architecture in a tissue or disease model.

With combinatorial indexing technology from ScaleBio, single-cell studies can be massively scaled to accomodate larger projects, expanding our knowledge of cell phenotypes in many areas of research.

The ScaleBio Single Cell RNA Sequencing Kit enables the preparation of up to 96 individual samples and a total of 125,000 cells per run, with an approachable, affordable 2-day workflow.

Cost-Effective

Multiplex up to 96 samples for increased throughput, reduced batch effects and > 50% lower cost per sample.

High Throughput

Profile 125,000 cells in one run.

Flexible Sample Preparation

Fix samples to store, transport and batch process samples for flexible, efficient experiments.

ScaleBio Single Cell RNA Sequencing Workflow

RNA-Product-Workflow-Fig

Single cell suspensions are fixed ahead of the workflow to process immediately or store for batch processing. Cells are then uniquely barcoded across three indexing steps to produce sequencing-ready single cell libraries.

High-throughput experiments without increasing multiplet rates

Graph depicting ScaleBio Single Cell RNA Sequencing's low multiplet rate of <5% while profiling 125,000 cells

Three levels of indexing ensure a low multiplet rate of <5% is maintained even while profiling 125,000 cells.

Publication
Ultra-high throughput single-cell analysis of proteins and RNAs by split-pool synthesis.

Commun Biol 3, 213 (2020).

Publication
Comprehensive single cell transcriptional profiling of a multicellular organism.

Science 357, 6352 (2017).

Publication
The single-cell transcriptional landscape of mammalian organogenesis.

Nature 566, 496-502 (2019).

Products for Single Cell Transcriptomics

Single-Cell-Library-Preparation-Kits-application@2x

Other applications